This course covers approaches for modelling treatment of infectious disease, as well as for modelling vaccination. Building on the SIR model, you will learn how to incorporate additional compartments to represent the effects of interventions, such the effect of vaccination in reducing susceptibility. You will learn about ‘leaky’ vaccines and how to model them, as well as different types of vaccine and treatment effects. It is important to consider basic relationships between models and data, so, using the basic SIR model you have developed in course 1, you will calibrate this model to epidemic data. Performing such a calibration by hand will help you gain an understanding of how model parameters can be adjusted in order to capture real-world data. Lastly in this course, you will learn about two simple approaches to computer-based model calibration - the least-squares approach and the maximum-likelihood approach; you will perform model calibrations under each of these approaches in R.
このコースについて
学習内容
Identify the relationship between models and real-world epidemiological data
Incorporate treatment or vaccination into an SIR model, accounting for imperfect efficacy, and for different mechanisms of action
Perform simple calibrations of an SIR model against time-series data, selecting parameters to maximise the fit of the model to the data
Recognise two simple approaches to computer-based model calibration and perform model calibrations under each of these approaches in R.
習得するスキル
- Mathematical Model
- Infectious Diseases
修士号の取得を目指しましょう
シラバス - 本コースの学習内容
Modelling Interventions
Confronting Models with Data - Part A
Confronting Models with Data - Part B
Confronting models with data – Part C
レビュー
- 5 stars75.51%
- 4 stars18.36%
- 3 stars2.04%
- 2 stars4.08%
INTERVENTIONS AND CALIBRATION からの人気レビュー
Such a great learning experience. The course provided me with a comprehensive overview of the topics under concern. My gratitude to the instructors for creating such a valuable course.
Very useful course.. I have learnt many things useful for my career
Stuck in last quiz for many hours, dig in many forums. Finally learn in-depth how and why model structure be like that. 5/5 would loss in thought again.
A great learning experience, have to struggle a lot for the quiz, But in the end it helps to get better understanding of the concept and practice.
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